Albendazole 400 mg is a broad-spectrum anthelmintic (anti-worm) medication used to treat various parasitic infections caused by worms, including tapeworms, roundworms, and hookworms. It works by inhibiting the growth and reproduction of parasites, ultimately killing them.
Active Ingredient:
- Albendazole 400 mg
Indications:
- Neurocysticercosis – Treats brain infections caused by pork tapeworm larvae (Taenia solium).
- Hydatid Disease (Echinococcosis) – Kills cysts caused by Echinococcus granulosus (dog tapeworm).
- Intestinal Parasitic Infections:
- Ascariasis (roundworm infection)
- Hookworm infection
- Trichuriasis (whipworm infection)
- Enterobiasis (pinworm infection)
- Giardiasis in Children – Used for certain protozoal infections.
- Strongyloidiasis – Treats Strongyloides stercoralis infections.
Key Features:
- Broad-Spectrum Anthelmintic – Effective against various parasitic worms.
- Single-Dose Treatment – For some infections, one dose is enough.
- Kills Both Larvae & Adult Worms – Prevents reinfection.
- Helps Prevent Malnutrition – Treats worms that cause nutritional deficiencies.
How to Use
- Dosage:
- For common worm infections: Single dose of 400 mg
- For neurocysticercosis & echinococcosis: 400 mg twice daily for 8–30 days (as prescribed).
- Administration:
- Take with food to enhance absorption.
- Can be chewed or swallowed whole with water.
- Repeat Dose: May be necessary after 2 weeks to fully clear the infection.
Precautions
- Avoid During Pregnancy – Can harm the developing fetus (use contraception while on treatment).
- Liver Disease Warning – Regular liver function monitoring is advised for long-term use.
- Bone Marrow Suppression (Rare) – Monitor blood counts if used for extended periods.
- Not for Children Under 2 Years – Consult a doctor for appropriate dosing.
Side Effects
Common Side Effects:
- Mild stomach pain
- Nausea or vomiting
- Dizziness or headache
- Temporary hair loss (rare)
Serious Side Effects (Rare):
- Liver toxicity (jaundice, yellowing of skin/eyes)
- Severe allergic reactions (rash, swelling, breathing difficulty)
- Low blood cell counts (weakness, frequent infections)
FAQ
-
How quickly does Albendazole 400 mg work?
- It starts working within a few hours, but worms may take several days to be fully expelled.
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Do I need to repeat the dose?
- For some infections, a second dose after 2 weeks is recommended to prevent reinfection.
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Can I take Albendazole on an empty stomach?
- For intestinal worms: Take on an empty stomach for best results.
- For systemic infections (e.g., hydatid disease, neurocysticercosis): Take with food for better absorption.
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Is Albendazole safe for children?
- Yes, but the dose may vary based on age and weight. Always consult a pediatrician before use.
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Can Albendazole be taken during pregnancy?
- No. It is not recommended in pregnancy, especially the first trimester.
Conclusion
Albendazole 400 mg is an effective anti-parasitic medication used for treating intestinal and systemic worm infections. It is usually taken as a single dose, but longer treatments may be needed for serious parasitic diseases. Always follow your doctor’s guidance for safe and effective use.
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