Asacol 400 mg contains Mesalazine (5-Aminosalicylic Acid), an anti-inflammatory medication used to treat and manage ulcerative colitis (UC) and Crohn’s disease. It helps reduce inflammation in the digestive tract, relieving symptoms such as diarrhea, rectal bleeding, and stomach pain.
Active Ingredient:
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Mesalazine (5-Aminosalicylic Acid) 400 mg
Indications:
- Ulcerative Colitis (UC): Helps manage mild to moderate cases and prevent flare-ups
- Crohn’s Disease: Reduces inflammation in the intestines
- Inflammatory Bowel Disease (IBD): Maintains remission and prevents relapse
Key Features:
- Targets Intestinal Inflammation: Directly works in the colon to reduce inflammation
- Long-Term Use: Helps maintain remission and prevent flare-ups
- Enteric-Coated Tablet: Ensures the drug is released where it is needed in the intestines
- Well-Tolerated: Fewer side effects compared to corticosteroids
How to Use
Administration:
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Take Asacol 400 mg with or without food, as directed by your doctor.
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Swallow whole with a glass of water. Do not crush, chew, or break the tablet to ensure proper release in the intestines.
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Take at the same time each day for best results.
Dosage:
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Active Ulcerative Colitis: 2.4g–4.8g daily (divided into doses)
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Maintenance of Remission: 1.6g–2.4g daily
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Crohn’s Disease: Dosage may vary based on severity, as prescribed
Missed Dose: Take as soon as you remember but skip if it’s close to the next dose. Do not double dose.
Important Notes:
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Do not stop taking Asacol suddenly without consulting your doctor, as symptoms may return.
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Drink plenty of water to prevent kidney issues.
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Regular kidney and liver function tests may be required during treatment.
Precautions
- Pregnancy & Breastfeeding: Use only if prescribed by a doctor.
- Kidney & Liver Disease: Requires medical supervision.
- Allergy Warning: Avoid if allergic to salicylates (e.g., aspirin).
Side Effects
Common Side Effects:
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Nausea, vomiting
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Headache
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Abdominal pain
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Diarrhea or constipation
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Flatulence (gas)
Rare but Serious Side Effects:
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Kidney problems (blood in urine, swelling, urination changes)
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Liver issues (yellowing of skin/eyes, dark urine)
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Severe allergic reactions (rash, itching, swelling, difficulty breathing)
FAQ
1. What is Asacol 400 mg used for?
Asacol is used to treat and prevent ulcerative colitis and Crohn’s disease flare-ups by reducing intestinal inflammation.
2. How long does it take for Asacol to work?
Improvement is usually seen within a few weeks, but full effects may take several months.
3. Can I take Asacol 400 mg with other medications?
Yes, but consult your doctor if taking NSAIDs, blood thinners, or immunosuppressants, as they may interact.
4. Can I stop taking Asacol if my symptoms improve?
No, stopping suddenly may cause symptoms to return. Always follow your doctor’s advice.
5. Is Asacol safe for long-term use?
Yes, it is often used for long-term maintenance to prevent relapses of ulcerative colitis.
6. Can I drink alcohol while taking Asacol?
Moderate alcohol consumption is usually fine, but excessive alcohol may worsen side effects.
7. Can Asacol cause weight gain?
Weight gain is not a common side effect, but changes in appetite may occur.
Conclusion
Asacol 400 mg is an effective and well-tolerated treatment for ulcerative colitis and Crohn’s disease. It reduces inflammation, prevents flare-ups, and supports long-term remission. Follow medical advice, stay hydrated, and take the medication as prescribed for the best results.
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