Duovir-E Kit is a combination antiretroviral therapy (ART) used for the treatment of HIV (Human Immunodeficiency Virus) infection. It contains three active ingredients: Lamivudine, Zidovudine, and Efavirenz, which work together to reduce the viral load in the body and improve immune function.
Active Ingredients
- Lamivudine (150 mg): A nucleoside reverse transcriptase inhibitor (NRTI) that prevents the virus from multiplying.
- Zidovudine (300 mg): Another NRTI that helps stop the replication of the HIV virus.
- Efavirenz (600 mg): A non-nucleoside reverse transcriptase inhibitor (NNRTI) that blocks the virus from growing.
Indications
- HIV-1 Infection: Used in combination therapy for managing and controlling HIV infection.
- Slows Disease Progression: Helps prevent complications such as AIDS (acquired immunodeficiency syndrome).
Key Features
- Triple-Drug Combination: Provides a comprehensive approach to HIV management.
- Reduces Viral Load: Helps lower the amount of HIV in the blood.
- Improves Immune Function: Boosts CD4 cell counts to enhance immunity.
- Convenient Fixed-Dose Therapy: Reduces the need for multiple pills.
How to Use
Administration:
- Take one kit (all tablets) orally once daily, preferably on an empty stomach before bedtime.
- Swallow each tablet with a glass of water.
- Avoid taking with high-fat meals, as this may increase Efavirenz-related side effects.
- Do not skip doses, as missing doses can lead to drug resistance.
Precautions
- Not a Cure for HIV: Helps manage the infection but does not eliminate the virus.
- Regular Monitoring: Requires periodic blood tests to monitor liver function, viral load, and immune response.
- Neurological Effects: Efavirenz may cause dizziness, drowsiness, or vivid dreams; avoid driving or operating heavy machinery if affected.
- Pregnancy and Breastfeeding: Should only be used under medical supervision during pregnancy. Breastfeeding is not recommended for HIV-positive mothers.
- Drug Interactions: Inform your doctor about any medications, including herbal supplements and other ART drugs.
Side Effects
Common Side Effects:
- Dizziness, drowsiness
- Nausea, vomiting
- Fatigue
- Rash
- Insomnia or vivid dreams
Serious Side Effects (Rare):
- Liver toxicity (yellowing of skin/eyes, dark urine)
- Severe mood changes or depression
- Lactic acidosis (muscle pain, breathing difficulty)
- Anemia (unusual tiredness, pale skin)
Frequently Asked Questions (FAQ)
1. What is Duovir-E Kit used for?
It is used to treat and manage HIV infection, helping lower viral load and improve immunity.
2. How long should I take Duovir-E Kit?
HIV treatment is lifelong, and adherence is crucial to prevent resistance and complications.
3. Can Duovir-E Kit be taken with food?
It is best taken on an empty stomach, as high-fat meals can increase Efavirenz-related side effects.
4. Does Duovir-E Kit cure HIV?
No, it helps control the virus but does not cure HIV.
5. Can I drink alcohol while taking Duovir-E Kit?
Avoid alcohol, as it may worsen side effects like dizziness and liver toxicity.
6. Does Duovir-E Kit affect mental health?
Efavirenz may cause mood changes, depression, or vivid dreams. Report any severe symptoms to your doctor.
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