Duovir N Tablet is a combination of Lamivudine (150mg), Zidovudine (300mg), and Nevirapine (200mg), used in the treatment of HIV (Human Immunodeficiency Virus) infection. It belongs to the antiretroviral drug class that helps in reducing viral load, improving immune function, and slowing down disease progression.
Key Benefits:
Helps manage HIV infection and prevents virus multiplication
Reduces the risk of developing AIDS and associated complications
Improves immune system function by increasing CD4 cell count
Prevents mother-to-child transmission of HIV during pregnancy
Combination therapy reduces resistance risk compared to single-drug treatments
How It Works:
Duovir N contains three antiretroviral drugs that work together:
- Lamivudine & Zidovudine – These are Nucleoside Reverse Transcriptase Inhibitors (NRTIs) that block the HIV enzyme reverse transcriptase, preventing the virus from replicating.
- Nevirapine – A Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) that directly inhibits viral replication.
Together, these drugs help control HIV, reduce viral load, and improve overall health.
How to Take Duovir N Tablet:
- Take orally, with or without food, as prescribed by your doctor.
- Swallow whole with water—do not crush or chew.
- Take at the same time daily for maximum effectiveness.
- Follow strict dosing instructions to prevent drug resistance.
- Do not stop suddenly, as it may worsen the infection.
Possible Side Effects:
- Nausea, vomiting, or diarrhea
- Headache or dizziness
- Fatigue or weakness
- Skin rash (common with Nevirapine, monitor closely)
- Loss of appetite or weight loss
- Anemia (low red blood cell count)
Serious but rare side effects include liver toxicity, severe skin reactions (Stevens-Johnson Syndrome), or neuropathy. Seek immediate medical help if severe reactions occur.
Precautions & Warnings:
Not a cure for HIV—it helps manage the virus but does not eliminate it.
Do not miss doses, as irregular use may cause drug resistance.
Monitor liver function regularly, as Nevirapine may cause liver damage.
Pregnant or breastfeeding women should consult a doctor before use.
Use effective contraception, as the medication may affect pregnancy safety.
Avoid alcohol, as it may increase the risk of liver toxicity.
Frequently Asked Questions (FAQs)
1. How long does Duovir N take to work?
It starts working within weeks, but full benefits are seen after months of continuous use.
2. Can Duovir N cure HIV?
No, it controls the virus but does not cure HIV. Lifelong treatment is required.
3. What should I do if I miss a dose?
Take it as soon as you remember but skip it if it’s close to the next dose—do not double up.
4. Can I take Duovir N with other medications?
Some antibiotics, antifungals, and painkillers may interact with Duovir N. Always inform your doctor about other medications.
5. Can Duovir N be taken during pregnancy?
It may be used in pregnancy to reduce the risk of mother-to-child transmission, but only under a doctor’s supervision.
6. Does Duovir N cause weight gain?
Weight changes may occur, but fat redistribution (lipodystrophy) is more common than weight gain.
7. Can I drink alcohol while taking Duovir N?
It is best to avoid alcohol, as it can worsen liver toxicity and side effects.
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