Ledifos Tablet

Ledifos Tablet is a combination of Ledipasvir (90 mg) and Sofosbuvir (400 mg), both of which are direct-acting antiviral (DAA) medications used to treat chronic hepatitis C virus (HCV) infection. It helps in preventing the virus from multiplying, ultimately leading to the elimination of HCV from the body.

Active Ingredients

• Ledipasvir (90 mg) – An NS5A inhibitor that stops viral replication.
• Sofosbuvir (400 mg) – An NS5B polymerase inhibitor that blocks viral multiplication.

Indications

• Treatment of chronic hepatitis C (HCV) infection
• Effective against HCV genotypes 1, 4, 5, and 6
• Helps prevent liver complications such as cirrhosis and liver cancer

Key Benefits

• Highly effective, with a cure rate of over 95% when used correctly
• Prevents liver damage and improves overall liver health
• When compared to previous HCV treatments, it is well tolerated with few side effects.
• Convenient once-daily dosing

Dosage & Administration

• Recommended dose: One tablet per day, with or without food
• The usual course is 12 to 24 weeks, depending on the patient’s condition and HCV genotype
• Do not skip doses as it may affect treatment success

Precautions

• Not recommended if a doctor doesn’t tell you to during pregnancy.
• Avoid alcohol, as it may worsen liver function
• Before using, patients with liver or kidney disease should talk to their doctor.
• Do not take with certain medications, including rifampin, amiodarone, and anticonvulsants

Possible Side Effects

Common Side Effects:

• Fatigue
• Headache
• Nausea
• Insomnia

Rare but Serious Side Effects:

• Severe allergic reactions
• Liver-related complications in patients with advanced liver disease

Frequently Asked Questions (FAQ)

1. Can Ledifos be used alone?
No, it is a combination medication, but it may need to be used with Ribavirin in some cases.

2. How effective is Ledifos Tablet?
It has a high cure rate of over 95%, especially for HCV genotypes 1 and 4.

3. Can I drink alcohol while taking Ledifos?
No, alcohol can worsen liver damage and reduce treatment effectiveness.

4. If I forget a dose, what should I do?
Take it as soon as you remember. If it’s close to your next dose, skip the missed dose—do not take a double dose.