Mesacol 400 mg contains Mesalamine (5-Aminosalicylic Acid), an anti-inflammatory drug used to treat ulcerative colitis and Crohn’s disease. It helps reduce inflammation in the intestines, relieving symptoms like diarrhea, rectal bleeding, and stomach pain.
Active Ingredient:
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Mesalamine (5-Aminosalicylic Acid) 400 mg
Indications:
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Ulcerative Colitis: Helps control inflammation in the colon
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Crohn’s Disease: Manages symptoms and prevents flare-ups
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Proctitis & Proctosigmoiditis: Reduces rectal and lower colon inflammation
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Maintenance Therapy: Prevents recurrence of symptoms
Key Features:
- Targeted Anti-Inflammatory Action: Works directly in the intestines to reduce inflammation
- Symptom Relief: Helps alleviate diarrhea, pain, and bleeding
- Long-Term Management: Suitable for maintenance therapy to prevent relapse
- Delayed-Release Tablets: Ensures the drug reaches the affected areas in the colon
How to Use
Administration:
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Swallow Mesacol 400 mg whole with a glass of water—do not chew, crush, or break the tablet.
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Can be taken with or without food, as advised by your doctor.
Dosage:
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Active Ulcerative Colitis: 800–2400 mg daily, divided into multiple doses.
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Maintenance Therapy: 1200–1600 mg per day, based on medical advice.
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Missed Dose: If a dose is missed, take it as soon as possible. If it’s close to the next dose, skip the missed one.  Do not double the dose.
Important Note:
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Consistent use is important for effective results.
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Do not stop taking Mesacol suddenly without consulting your doctor.
Precautions
Kidney & Liver Function: Regular monitoring may be required.
Pregnancy & Breastfeeding: Consult a doctor before use.
Hydration: Drink plenty of fluids to prevent kidney-related side effects.
Allergies: Avoid if allergic to salicylates (e.g., aspirin).
Side Effects
Common Side Effects:
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Nausea, vomiting
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Headache
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Abdominal pain, bloating
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Diarrhea or constipation
Rare but Serious Side Effects:
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Kidney problems (changes in urination, swelling, fatigue)
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Severe allergic reactions (rash, swelling, breathing difficulty)
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Liver enzyme changes (yellowing of skin/eyes, dark urine)
FAQ
1. What is Mesacol 400 mg used for?
Mesacol is used to treat ulcerative colitis, Crohn’s disease, and proctitis by reducing inflammation in the intestines.
2. How does Mesalamine work?
It reduces inflammation in the intestines by inhibiting the production of inflammatory chemicals.
3. How should I take Mesacol?
Swallow it whole with water, do not crush or chew it. Follow the doctor’s prescribed dosage.
4. Can Mesacol cure ulcerative colitis?
No, but it helps manage and control symptoms, preventing flare-ups.
5. Is Mesacol safe during pregnancy?
It is generally considered safe during pregnancy but consult your doctor before use.
6. How long does it take for Mesacol to work?
Most patients notice improvement within a few weeks, but full benefits may take longer.
7. Can I stop taking Mesacol if my symptoms improve?
No, stopping suddenly can cause a relapse. Always consult your doctor before discontinuing.
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