Oxramet XR 10/1000mg

Oxramet XR 10/1000mg is an antidiabetic medication that combines Dapagliflozin (10mg) and Metformin Hydrochloride Extended-Release (1000mg). It is used to manage Type 2 Diabetes Mellitus (T2DM) by improving blood sugar control in adults. This combination helps lower blood glucose levels effectively while reducing the risk of complications associated with diabetes.

Active Ingredients:

• Dapagliflozin 10mg (SGLT2 inhibitor)
• Metformin Hydrochloride 1000mg (Extended-Release) (Biguanide)

Indications:

• Type 2 Diabetes Mellitus (T2DM) – Used in patients who need better blood sugar control.
• Improves Insulin Sensitivity – Helps the body use insulin more efficiently.
• Reduces Risk of Cardiovascular Complications – Beneficial for patients with diabetes and heart disease.
• Weight Management – Dapagliflozin helps in weight loss by reducing excess glucose.

Key Features:

• Dual Action for Better Blood Sugar Control – Works on different mechanisms to regulate glucose levels.
• Extended-Release Formulation – Provides long-lasting effect with once-daily dosing.
• Weight & Blood Pressure Benefits – Helps in weight management and may lower blood pressure.
• Reduces Risk of Hypoglycemia – Lower chances of dangerously low blood sugar levels.

How to Use

Administration:

• Take once daily with food, preferably in the evening, to reduce stomach upset.
• Swallow the tablet whole with water; do not crush or chew.
• Maintain a healthy diet and exercise routine while on medication.

Dosage:

• The dose is determined based on individual needs and doctor’s advice.
• Usual starting dose: One tablet (10/1000mg) once daily.
• Dose adjustments depend on blood sugar levels and kidney function.

Precautions

• Kidney Function: Avoid use in patients with severe kidney impairment.
• Dehydration Risk: Dapagliflozin may cause increased urination, leading to dehydration.
• Lactic Acidosis: Metformin may rarely cause a serious condition called lactic acidosis.
• Urinary Tract Infections (UTI): Dapagliflozin increases the risk of UTIs and genital infections.
• Avoid Alcohol: May increase the risk of lactic acidosis and low blood sugar.
• Not for Type 1 Diabetes or Diabetic Ketoacidosis (DKA).

Side Effects

Common Side Effects:

• Nausea, vomiting
• Diarrhea
• Increased urination
• Fatigue
• Mild dizziness

Serious Side Effects (Rare):

• Lactic acidosis (Metformin-related) – Symptoms: muscle pain, weakness, difficulty breathing
• Severe dehydration – Symptoms: excessive thirst, lightheadedness
• Urinary tract infections (UTI) – Symptoms: pain while urinating, fever
• Ketoacidosis (Dapagliflozin-related) – Symptoms: nausea, vomiting, abdominal pain, rapid breathing

FAQ

1. What is Oxramet XR 10/1000mg used for?

   • It is used to control blood sugar levels in Type 2 Diabetes Mellitus patients.

2. Can Oxramet XR help with weight loss?

   • Yes, Dapagliflozin promotes weight loss by removing excess glucose through urine.

3. How long does it take to see results?

   • Blood sugar levels start improving within a few weeks, but full benefits take time.

4. Can I take Oxramet XR with other diabetes medications?

   • Yes, it can be combined with insulin or other oral diabetes drugs, as prescribed by a doctor.

5. Is Oxramet XR safe for kidney patients?

   • It should be avoided in severe kidney disease; consult your doctor for alternatives.

6. What should I do if I miss a dose?

   • Take it as soon as you remember but skip it if it’s almost time for the next dose. Never double dose.

7. Can I drink alcohol while taking this medication?

   • Avoid alcohol, as it can increase the risk of lactic acidosis and dehydration.