SYNCAPONE 50mg Tablet 10’s

SYNCAPONE 50mg Tablet contains Entacapone, a COMT (Catechol-O-methyltransferase) inhibitor, used as an adjunctive treatment in the management of Parkinson’s disease. Parkinson’s disease is a neurodegenerative disorder that results in the progressive loss of dopamine-producing neurons, leading to symptoms such as tremors, rigidity, bradykinesia (slowness of movement), and postural instability.

Entacapone works by inhibiting the COMT enzyme, which normally breaks down Levodopa (another Parkinson’s medication) in the body before it can reach the brain. By blocking this enzyme, SYNCAPONE helps increase the availability of Levodopa in the brain, thus improving the effectiveness of Levodopa therapy and helping to reduce motor fluctuations in people with Parkinson’s disease.

SYNCAPONE is commonly used in combination with Levodopa and Carbidopa, another Parkinson’s medication, to enhance the overall treatment outcome.

Key Benefits

• Improves effectiveness of Levodopa therapy by preventing the breakdown of Levodopa before it reaches the brain.
• Reduces motor fluctuations such as “wearing off” or “on-off” episodes that occur with Levodopa therapy.
• Helps to manage symptoms of Parkinson’s disease, such as tremors, rigidity, and bradykinesia.
• Prolongs the benefits of Levodopa treatment by ensuring that more of the medication is available to the brain for a longer period.
• Well, tolerated in combination with Levodopa and Carbidopa.

How It Works

SYNCAPONE contains Entacapone, which works by inhibiting the COMT enzyme. This enzyme normally breaks down Levodopa into other inactive compounds, reducing its effectiveness. By blocking COMT, Entacapone increases the bioavailability of Levodopa, allowing more of it to reach the brain, where it is converted into dopamine to help control motor symptoms. This results in improved motor function and reduced fluctuations associated with Parkinson’s disease treatment.

Entacapone also helps extend the action of Levodopa, making the medication’s effects last longer throughout the day.

How to Use

• Dosage: The typical dose of SYNCAPONE is 1 tablet (50mg) taken with each dose of Levodopa/Carbidopa. The exact dosage will depend on the individual’s needs and doctor’s prescription.
• Administration: Take SYNCAPONE with or without food, but always follow your doctor’s instructions regarding timing and dosage.
• It is important not to exceed the prescribed dose as it may lead to adverse effects.
• Consult your doctor to determine the proper combination and dosing schedule for your condition.

Possible Side Effects

• Common Side Effects:

  • Diarrhea
  • Nausea
  • Stomach pain or discomfort
  • Fatigue
  • Dizziness
  • Uncontrolled body movements (dyskinesia)

• Serious but Rare Side Effects:

  • Liver problems (yellowing of skin or eyes, dark urine)
  • Severe nausea or vomiting
  • Mental or mood changes (confusion, hallucinations)
  • Sudden, severe weakness or muscle pain
  • Heart palpitations or chest pain

FAQs

1. What is SYNCAPONE used for?
SYNCAPONE is used in combination with Levodopa and Carbidopa to treat Parkinson’s disease. It helps to increase the effectiveness of Levodopa by preventing its breakdown in the body, improving motor function and reducing motor fluctuations.

2. How does SYNCAPONE work?
SYNCAPONE contains Entacapone, which blocks the COMT enzyme. This enzyme normally breaks down Levodopa, but by inhibiting it, SYNCAPONE ensures that more Levodopa reaches the brain, where it can be converted into dopamine.

3. Can SYNCAPONE be taken alone?
No, SYNCAPONE is usually prescribed in combination with Levodopa and Carbidopa for the treatment of Parkinson’s disease. It is not effective on its own.

4. How should I take SYNCAPONE?
SYNCAPONE should be taken with each dose of Levodopa/Carbidopa as prescribed by your doctor. Typically, it is taken one tablet (50mg) with each dose of your Parkinson’s medication.

5. Are there any dietary restrictions when taking SYNCAPONE?
There are no specific dietary restrictions with SYNCAPONE, but you should follow your doctor’s recommendations regarding meals and medications, particularly with respect to Levodopa.

6. What should I do if I miss a dose?
If you miss a dose of SYNCAPONE, take it as soon as you remember, but never take two doses at once. Follow your regular schedule and consult your doctor if you have concerns.