Water for Injection (WFI) is a sterile, non-pyrogenic, and purified form of water used for diluting or dissolving drugs before administration by injection. It is free from any added substances and is used to ensure the safe and effective preparation of injectable medications.
Uses & Benefits
- Dilution of Injectable Medications – Used to dissolve or dilute drugs before administration.
- Reconstitution of Powdered Medicines – Helps mix lyophilized (freeze-dried) medications.
- Medical and Laboratory Use – Used in hospitals and labs for sterile procedures.
How to Use
- Administered only as directed by a healthcare professional.
- It is not for direct injection unless mixed with a suitable drug.
- Used as a solvent for intravenous (IV), intramuscular (IM), or subcutaneous (SC) injections.
Precautions & Warnings
- Not for Direct Injection – Must be mixed with a compatible drug before use.
- Sterility is Essential – Use immediately after opening; discard unused portions.
- Avoid Contamination – Use a sterile syringe and needle.
- Storage Conditions – Keep at room temperature in a dry place.
Possible Side Effects
 Generally safe when used correctly, but improper use may lead to:
- Pain at the injection site
- Infection if sterility is compromised
- Electrolyte imbalance (if used in large amounts without proper formulation)
Frequently Asked Questions (FAQs)
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Can I inject Water for Injection directly?
- No, it must be mixed with a suitable drug before injection.
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Is WFI the same as distilled water?
- No, WFI is sterile, non-pyrogenic, and specifically purified for medical use.
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How should I store Water for Injection?
- Store in a cool, dry place away from direct sunlight.
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Can I use WFI for wound cleaning?
- No, it is meant for injection purposes. Use sterile saline for wound cleaning.
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Can I reuse an opened WFI vial?
- No, once opened, it should be used immediately, and any remaining liquid should be discarded.
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